Rootine

 Magnesium, Calcium, Zinc, Manganese, Copper, Iron, Selenium

 Phytosterols, Alpha Lipoic Acid, MSM, CoQ10, Omega-3s ($10/month)

B2, B6, B9 (Folate), B12, D3, C, E, Magnesium, Calcium, Zinc, Manganese, Copper, Iron, Selenium, Phytosterols, Alpha Lipoic Acid, MSM, CoQ10, and Omega-3s.

What vitamins and minerals do you offer?

We focus on nutrients with 1) clinical backing and 2) clear gene-nutrient interaction. We’re always working to expand our offering, and most recently began including Omega 3s. If there is a nutrient important to your daily regimen, please send us a note to hello@rootine.co. We’re happy to keep you updated on the current status within our research and development.

We focus on nutrients with 1) clinical backing and 2) clear gene-nutrient interaction.

Why don’t you currently offer ___? 

This is the industry-leading format we've developed to deliver your vitamins, minerals, and other nutrients in the best way possible.Our plant-based microbeads contain primarily natural & 100% vegetarian ingredients. Each microbead is made of pure, raw ingredients, and coated with natural, sustainably-farmed beeswax. We focus on what you need and avoid unnecessary fillers, artificial colors, and other useless ingredients that big supplement companies include in their vitamins.

Our microbeads provide precision dosing and personalized formulations.

Our microbeads are slow-release, providing a steady release of nutrients throughout the day.

Our microbeads allow for us to include a full range of nutrients in your pack with no absorption interference (e.g. calcium and zinc).

Each microbead is made of pure, raw ingredients, and coated with natural, sustainably-farmed beeswax.

What are microbeads?

We look at both the C677T and A1298C MTHFR mutations with our test and/or analysis of raw data. Depending on the mutation combination you carry (there are 6 possible combinations) we dose your daily pack with a ratio of folic acid : methylfolate that corresponds to the activity of your MTHFR enzyme.

That being said, we can always remove Folic Acid upon request. We wrote a blog post as well if you'd like to read further into our method and approach:

We dose your daily pack with a ratio of folic acid: methylfolate that corresponds to the activity of your MTHFR enzyme. However, we can always remove Folic Acid upon request.

Folic Acid vs. Methylfolate

The microbeads were developed over 3+ years to provide the capability to offer precision nutrient dosing (to the mg or mcg) while simultaneously offering premier absorption properties. The microbeads are made from the raw nutrient, pharmaceutical grade cellulose and starch (this forms the slow release matrix), and coated in sustainably-farmed beeswax. Each microbeads undergoes rigorous testing during the research & development phase and additional quality, potency, and purity testing during production phases. The 6+ hour sustained-release nature of the microbead helps maintain optimal blood nutrient levels throughout the day while simultaneously providing time- and spatial-nutrient separation to ensure optimal uptake.

Microbeads were developed over 3+ years to provide the capability to offer precision nutrient dosing. Each microbeads undergoes rigorous testing during the research & development phase.

History of microbeads

Microbeads enable us to mix any micronutrient formula quickly and accurately.The nutrients encapsulated by the microbeads are better protected from oxygen and remain stable for longer periods of time compared to liquid preparations or powdered forms. 

Absorption: Microbeads provide optimal nutrient absorption using a slow-release format. Nutrients are delivered throughout the day in small doses, in comparison to a large dose all at once seen in most form factors.

Nutrient interaction: The microbead system also prevents issues related to contraindicated nutrients (e.g. calcium and zinc) due to time and spatial nutrient separation. For example, calcium and zinc use the same uptake channels during absorption. When large amounts of these nutrients are introduced into the intestine at one time (common with dietary supplements) the uptake channels are overwhelmed and absorption is negatively affected.

Microbeads provide optimal nutrient absorption using a slow-release format. They also prevent issues related to contraindicated nutrients due to time and spatial nutrient separation.

What are the benefits of microbeads?

That is correct, it is a matrix we developed that slowly releases nutrients in the intestine (average 6+ hour dissolution rate). The slow-release method helps improve nutrient uptake, reduces uptake channel competition, and helps maintain optimal blood levels over time. Cellulose is the carbohydrate the makes up the plant cell wall and is not absorbed (it is a fiber).

That is correct, it is a matrix we developed that slowly releases nutrients in the intestine. This  improves nutrient uptake, reduces uptake channel competition, and helps maintain optimal blood levels over time.

I read that your product uses a cellulose matrix to help with absorption. Is that correct?

Our ingredients are sourced by our co-founder Dr. Daniel Wallerstorfer PhD. All vendors are heavily vetted prior to acceptance and then routinely audited with additional testing on raws, as well as extensive testing that we have throughout our microbead process and finished product.

We are not able to disclose the full list of our suppliers; however, the majority of the vendors are of EU origin as we have found the EU has the strictest laws / best practices and thus often the best raw materials come from these sources. You can see the specific sources of each nutrient we offer here: 

The majority of the vendors are of EU origin as we have found the EU has the strictest laws / best practices and thus often the best raw materials come from these sources.

Where are your nutrients sourced from?

When selecting the raw materials, we place great emphasis on quality. Where possible, we give preference to biological sources of micronutrients and microbead constituents. The microbeads consist of indigestible vegetable fibers and we obtain nutrients from pristine and efficacious sources, like calcium from calcified algae cultivated in clean waters around Iceland, biological magnesium filtered from seawater, and phytosterols from soy-free pine. These nutrients are sourced by Dr. Daniel Wallerstorfer PhD and undergo rigorous quality and purity testing. Approximately 90% of the nutrients in your daily pack are of natural origin. This may vary slightly due to your unique formulation.

Where possible, we give preference to biological sources of micronutrients and microbead constituents.

Natural raw materials

Taking microbeads is easy once you get the hang of it. You have two options:

With Water - First, tear off the small white strip from the pre-cut notch. Next, cup your tongue to catch the microbeads and pour about half of the packet onto your tongue. Finally, purse your lips to a cup of water and (this part takes some practice) simultaneously sip the water into your mouth while swallowing the microbeads. Repeat until packet is gone.

On Food - Open the packet by tearing from the pre-cut notch and pour the microbeads onto your favorite food. We love stir them in yogurt, chia pudding, and pre-blended smoothies.

Remember, you don't want to bite, chew, or blend the microbeads.

 An intact microbead is flavorless but a crushed microbead is not! Also, we don't recommend pouring the microbeads into a glass of water. They sink to the bottom and stick to the sides.

You have two options: with water or on food. You don't want to bite, chew, or blend the microbeads.

How do I take microbeads? 

Some active ingredients that we require are not readily available from natural sources or would require unethical sourcing. In these cases, we use pharmaceutically manufactured micronutrients to ensure that our customers receive optimal nutrient efficacy and safety. In addition, these micronutrients remain stable for longer and are particularly pure. Our laboratory produced raw materials are first-class quality, undergo rigorous testing, and sourced by Dr. Wallerstorfer PhD.Your packet contains approximately 10% pharmaceutically produced nutrients. This may vary slightly due to your unique formulation.

Some active ingredients that we require are not readily available from natural sources or would require unethical sourcing. In these cases, we use pharmaceutically manufactured micronutrients to ensure that our customers receive optimal nutrient efficacy and safety.

Pharmaceutically-produced raw materials 

Rootine’s Chief Scientist Officer and Co-Founder, Dr. Daniel Wallerstorfer, PhD handles all raw-material sourcing, and focuses on finding the most natural and bio-available products available. All testing, manufacturing, and product development is completed at our licensed medical-grade genetics laboratory. The lab carries ISO 9001, 15189, and 22000 certifications, follows all FDA Current Good Manufacturing Practices (cGMP), completes rigorous in-house and 3rd party testing, and participates in an inter laboratory proficiency program to ensure accurate genetic testing results. We test new supplier shipments for toxins, heavy metals, bacteriology and vitamin content, and continue to do this until we are assured of their quality. We then perform random shipment testing (vitamin content and bacteriology) and additional testing on more sensitive substances (e.g. compounds that have a low stability). We perform all necessary tests to determine the stability of each nutrient in pellet form, and this testing is completed for every substance. As an additional measure to maximize stability, we frequently produce small batches of pellets to minimize the time between production and consumer use.

The lab carries ISO 9001, 15189, and 22000 certifications, follows all FDA Current Good Manufacturing Practices (cGMP), completes rigorous in-house and 3rd party testing, and participates in an inter laboratory proficiency program to ensure accurate genetic testing results.

Quality

We adhere to EFSA-described nutrients to ensure our customers receive a formula exclusively comprised of nutrients with a proven, long-standing efficacy and safety profile in humans. In addition, we choose nutrient forms that have the largest volume of literature backing their use. As new literature and mechanistic understanding of nutrients forms advances, we continue to update and reformulate our suite of microbeads

We adhere to EFSA-described nutrients to ensure our customers receive a formula exclusively comprised of nutrients with a proven, long-standing efficacy and safety profile in humans.

Microbeads and Nutrients